+7 (495) 624-5749

Laboratory of methods and instrumentation for microorganisms studies

The Head - Grigory V. Kotelnikov, PhD
+7 (4967) 31-8940

Photos of the laboratory

The lab was founded in 1965 and started its work with development of equipment for continuous cultivation of mictroorganisms ANKUM-1 (supervisor - academician N.D. Ierusalimski). Currently the lab developes both equipment for cultivation of microorganisms and instrumentation for physico-chemical studies.

Before 1980 the lab developed separate instruments for cultivation of microorganisms: ANKUM-2, ANKUM-2M, AK-3, AK-10, AK-203, AK-210. Since 1980 the lab develops automated systems: instrumentation for continuous cultivation of microorganisms, "Fermenter-PEVM" system, ANKUM-3 and so on. In these systems various physico-chemical parameters of cultivation processes are controlled by a computer.

The lab develops scanning and isothermal titration microcalorimeters. We have developed a new method of isothermat titration microcalorimetry for microsamples, a method of allocation of sensitive volume of calorimetric cells of a titration calorimeter by means of the thermal bridging. These findings were used in the development of the isothermal titration calorimeter KTD-101.

The scanning calorimetry method was used to construct a fermenter ANKUM-3 with a calorimetric mass-meter, which is used for computer control of the mass of culture fluid in the instrument.

Principal publications of the lab

  • Kotelnikov G.V., Moiseyeva S.P., Mezhburd E.V. and Krayev V.P. New isothermal titration calorimeter for investigations on very small samples. Theoretical and experimental studies. J. Thermal Analysis and Calorimetry, 2002, 68, 803-818.
  • Kotelnikov G.V., Moiseyeva S.P., Mezhburd E.V. and Krayev V.P. Method of separating the sensitive volume of calorimetric cells in a differential titration calorimeter. J. Thermal Analysis and Calorimetry, 2000, 62, 39-50.
  • Kotelnikov G.V. et al. Calorimetric method for adjusting the mass of culture fluid in a bioreactor, Review Sci. Instr. 1998, 69, 5, 2137-2140.
  • Kotelnikov G.V., and Sidorovich A.V. Microcalorimeter DSM-2 in polymers studies. High-polymeric compounds (Moscow) 1983, XXV, 12, 2622-2626.
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